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anti-Human PRKACG Antibodies:
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Human Polyclonal PRKACG Primary Antibody for ELISA, WB - ABIN562372
Adachi, Kano, Saido, Murata: Visual screening and analysis for kinase-regulated membrane trafficking pathways that are involved in extensive beta-amyloid secretion. in Genes to cells : devoted to molecular & cellular mechanisms 2009
Human Monoclonal PRKACG Primary Antibody for FACS, IHC - ABIN969365
Louiset, Stratakis, Perraudin, Griffin, Libé, Cabrol, Fève, Young, Groussin, Bertherat, Lefebvre et al.: The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on ... in The Journal of clinical endocrinology and metabolism 2009
The missense p.74Ile>Met PRKACG mutation is associated with a marked defect in proplatelet formation and a low level in filamin A in megakaryocytes.
Results suggest that PKA can negatively regulate ERalpha, at least in part, through FoxH1.
PKA-mediated phosphorylation of GPIbbeta at Ser(166) negatively regulates VWF binding to GPIb-IX and is one of the mechanisms by which PKA mediates platelet inhibition
Results suggest that Cgamma and Calpha differ in structure and function in vitro, supporting the hypothesis that functionally different C-subunit isozymes could affect cAMP signal transduction downstream of protein kinase A activation.
In human primary pigmented nodular adrenocortical disease tissues, dexamethasone paradoxically stimulates cortisol release through a glucocorticoid receptor-mediated effect on PKA catalytic subunits.
Findings show that PKIB and PKA-C kinase can have critical functions of aggressive phenotype of PCs through Akt phosphorylation and that they should be a promising molecular target for PC treatment.
Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit.
, cAMP-dependent protein kinase catalytic subunit gamma
, serine(threonine) protein kinase
, protein kinase, cAMP-dependent, catalytic, gamma