SHQ1 antibody (N-Term)

Catalog No. ABIN1077373

Product Details anti-SHQ1 Antibody

Target: SHQ1 (SHQ1 Homolog (SHQ1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHQ1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: Multiple isoforms are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogen: SHQ1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SHQ1.

Isotype: IgG

Application Details

Application Notes: SHQ1 antibody can be used for detection of SHQ1 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.

Comment:

(NT) human homolog of yeast SHQ1p

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: SHQ1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for SHQ1

Target: SHQ1 (SHQ1 Homolog (SHQ1))

Alternative Name: SHQ1 (SHQ1 Products)

Synonyms: 2810403P18Rik antibody, Grim-1 antibody, zgc:158255 antibody, Shq1p antibody, SHQ1 homolog (S. cerevisiae) antibody, SHQ1, H/ACA ribonucleoprotein assembly factor antibody, Shq1 antibody, SHQ1 antibody, shq1 antibody

Background: SHQ1 is the human homolog of yeast Shq1p, a protein that acts as an accessory factor in the assembly of H/ACA ribonucleoproteins. SHQ1 has been shown to bind the major H/ACA core protein and the pseudouridine synthase NAP57, but precedes the assembly role of NAF1 and of the other H/ACA core proteins. SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase.
Synonyms: Shq1p, FLJ10539

Molecular Weight: 63 kDa

Gene ID: 55164

NCBI Accession: NP_060600

Pathways: Ribonucleoprotein Complex Subunit Organization