SHQ1 antibody (N-Term)

Catalog No. ABIN6991751

Product Details anti-SHQ1 Antibody

Target: SHQ1 (SHQ1 Homolog (SHQ1))

Binding Specificity: AA 80-130, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHQ1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: Multiple isoforms are known to exist.

Purification: SHQ1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SHQ1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SHQ1. The immunogen is located within amino acids 80 - 130 of SHQ1.

Isotype: IgG

Application Details

Application Notes: SHQ1 antibody can be used for detection of SHQ1 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SHQ1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SHQ1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SHQ1

Target: SHQ1 (SHQ1 Homolog (SHQ1))

Alternative Name: SHQ1 (SHQ1 Products)

Synonyms: 2810403P18Rik antibody, Grim-1 antibody, zgc:158255 antibody, Shq1p antibody, SHQ1 homolog (S. cerevisiae) antibody, SHQ1, H/ACA ribonucleoprotein assembly factor antibody, Shq1 antibody, SHQ1 antibody, shq1 antibody

Background: SHQ1 Antibody: SHQ1 is the human homolog of yeast Shq1p, a protein that acts as an accessory factor in the assembly of H/ACA ribonucleoproteins. SHQ1 has been shown to bind the major H/ACA core protein and the pseudouridine synthase NAP57, but precedes the assembly role of NAF1 and of the other H/ACA core proteins. SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase.

Molecular Weight: 63 kDa

Gene ID: 55164

NCBI Accession: NP_060600

UniProt: Q6PI26

Pathways: Ribonucleoprotein Complex Subunit Organization