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Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2) (C-Term) antibody Primary Antibody

CMPK2 Reactivity: Human, Mouse, Rat IF, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1077386
$380.00
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0.1 mg ABIN1077386
0.1 mg ABIN1077386
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  • Target
    Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2)
    Binding Specificity
    C-Term
    • 9
    • 9
    • 7
    • 7
    • 5
    • 1
    Reactivity
    Human, Mouse, Rat
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    Un-conjugated
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Application
    Immunofluorescence (IF), ELISA, Western Blotting (WB)
    • 24
    • 17
    • 16
    • 16
    • 4
    • 1
    • 1
    • 1
    Specificity
    Multiple isoforms of CMPK2 are known to exist.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2.
    Isotype
    IgG
  • Application Notes
    CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
    Comment

    (CT) Cytidine monophosphate (UMP-CMP) kinase 2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS containing 0.02 % Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Storage
    4 °C
    Storage Comment
    CMPK2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
    Expiry Date
    12 months
  • Target
    Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2)
    Alternative Name
    CMPK2 (CMPK2 Antibody Abstract)
    Synonyms
    si:ch211-276e8.3, TMPK2, TYKi, UMP-CMPK2, 1200004E04Rik, TDKI, Tyki, cytidine/uridine monophosphate kinase 2, cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial, CMPK2, cmpk2, Cmpk2
    Background
    UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
    Synonyms: Cytidine monophosphate (UMP-CMP) kinase 2, TMPK2, TYKi, UMP-CMPK2
    Molecular Weight
    49 kDa
    Gene ID
    129607
    NCBI Accession
    NP_997198
    Pathways
    Nucleotide Phosphorylation, Cellular Response to Molecule of Bacterial Origin
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