Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2) (C-Term) antibody

Details for Product No. ABIN1077386
Target
Binding Specificity
C-Term
8
8
7
7
5
1
Reactivity
Human, Mouse, Rat
23
2
2
1
1
1
1
1
1
1
Host
Rabbit
22
1
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunofluorescence (IF), ELISA, Western Blotting (WB)
23
17
16
15
3
1
1
1
Options
Immunogen CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2.
Blocking Peptide Blocking peptide for this product available: ABIN1383482
Isotype IgG
Specificity Multiple isoforms of CMPK2 are known to exist.
Purification Affinity chromatography purified via peptide column
Target
Alternative Name CMPK2 (CMPK2 Antibody Abstract)
Background UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
Synonyms: Cytidine monophosphate (UMP-CMP) kinase 2, TMPK2, TYKi, UMP-CMPK2
Molecular Weight 49 kDa
Gene ID 129607
NCBI Accession NP_997198
Pathways Nucleotide Phosphorylation, Cellular Response to Molecule of Bacterial Origin
Application Notes CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Comment

(CT) Cytidine monophosphate (UMP-CMP) kinase 2

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS containing 0.02 % Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage 4 °C
Storage Comment CMPK2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
Expiry Date 12 months
Images
Image no. 1 for anti-Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2) (C-Term) antibody (ABIN1077386) anti-Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2) (C-Term) antibody