MRGPRC antibody (N-Term)

Catalog No. ABIN1108300

Product Details anti-MRGPRC Antibody

Target: MRGPRC (MAS-Related G-Protein Coupled Receptor, Member C (MRGPRC))

Binding Specificity: AA 14-28, N-Term

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGPRC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects MRGPRC (14-28).

Cross-Reactivity (Details): Species reactivity (tested):Rat

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of rat MRGPRC (14-28 amino acid)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for MRGPRC

Target: MRGPRC (MAS-Related G-Protein Coupled Receptor, Member C (MRGPRC))

Alternative Name: MRGPRC (MRGPRC Products)

Background: MAS-related G-protein coupled receptor, member C, also known as MRGPRC or MRGPRX1, is a human gene. The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans contain a related but nonorthologous family of genes, called MrgXs or sensory neuron-specific receptors, of which many fewer appear to be expressed in sensory neurons.Synonyms: Mas-related G-protein coupled receptor member X1, Mrgc, Mrgprc11, Mrgprx1, Sensory neuron-specific G-protein coupled receptor 1, Snsr, Snsr1

Gene ID: 282547

NCBI Accession: NP_001002286

UniProt: Q8R4G1