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UBXN6 antibody

This anti-UBXN6 antibody is a Mouse Monoclonal antibody detecting UBXN6 in WB, IF and IP. Suitable for Human.
Catalog No. ABIN1381743

Quick Overview for UBXN6 antibody (ABIN1381743)

Target

See all UBXN6 Antibodies
UBXN6 (UBX Domain Protein 6 (UBXN6))

Reactivity

  • 24
  • 15
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 23
  • 1
Mouse

Clonality

  • 23
  • 1
Monoclonal

Conjugate

  • 15
  • 3
  • 2
  • 2
  • 1
  • 1
This UBXN6 antibody is un-conjugated

Application

  • 19
  • 15
  • 14
  • 4
  • 3
  • 2
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone

5C3-1
  • Specificity

    Detects both isoforms

    No Cross-Reactivity

    Mouse (Murine)

    Purification

    purified

    Immunogen

    recombinant protein purified from bacteria

    Isotype

    IgG1
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    0.5 % PBS, 50 % glycerol, 0.1 % BSA

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C

    Storage Comment

    short term: 2 °C - 8 °C, long term: -20 °C
  • Target

    UBXN6 (UBX Domain Protein 6 (UBXN6))

    Alternative Name

    UBXD1 (Full Length and Short Isoform)

    Background

    P97 is a highly abundant and conserved member of the AAA family of ATPase. It has been termed an ubiquitin selective chaperone as it functions within the ubiquitin and/or proteasome pathway. p97 does not interact with ubiquitinated substrates on its own, but requires specific adapters that interact with ubiquitinated substrates and p97 and recruits p97 to substrates. One family of adapters contains a UBX domain, which has been shown with certain adapters to function as a p97-binding module. UBXD1 is a UBX domain containing protein and p97 adapter. This adapter is unique in that it does not harbor an ubiquitin association domain and binds p97 via its PUG domain (another p97 binding motif). Two isoforms of UBXD1 are produced in cells, a full-length form of approximately 54 kDa, and an alternatively spliced variant that lacks the amino-terminal translational start site, and encodes a 47 kDa protein that is derived from an internal translational initiation site. UBXD1 expression at the RNA level has been shown to trend lower in poor prognostic cancers, including those of the breast and prostate.

    UniProt

    Q9BZV1
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