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TNFRSF10A antibody

TNFRSF10A Reactivity: Human WB, IP Host: Mouse Monoclonal B-N28 unconjugated
Catalog No. ABIN1383733
  • Target See all TNFRSF10A Antibodies
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    Reactivity
    • 75
    • 5
    • 3
    • 1
    • 1
    Human
    Host
    • 38
    • 37
    Mouse
    Clonality
    • 40
    • 35
    Monoclonal
    Conjugate
    • 41
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF10A antibody is un-conjugated
    Application
    • 33
    • 32
    • 19
    • 18
    • 17
    • 12
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Specificity
    Recognises a 43-46 kDa protein
    Purification
    Ion exchange chromatography
    Sterility
    0.22 μm filtered
    Immunogen
    Recombinant human TRAIL R1/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells
    Clone
    B-N28
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TNFRSF10A Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    Preservative
    Without preservative
    Storage
    4 °C
    Storage Comment
    Stable at +2-8°C for 12 months
  • Lin, Chen, Yue, Zou, Benbrook, Liu, Le, Berlin, Khuri, Sun: "CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells." in: Cancer research, Vol. 68, Issue 13, pp. 5335-44, (2008) (PubMed).

    Raja, Chen, Yue, Acker, Lefkove, Arbiser, Khuri, Sun: "The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis." in: Molecular cancer therapeutics, Vol. 7, Issue 7, pp. 2212-23, (2008) (PubMed).

    Chen, Liu, Yue, Schönthal, Khuri, Sun et al.: "CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of ..." in: Molecular pharmacology, Vol. 72, Issue 5, pp. 1269-79, (2007) (PubMed).

    Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

  • Target
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    Alternative Name
    TRAIL R1 (TNFRSF10A Products)
    Background
    DR4, TRAIL R1
    Molecular Weight
    43-46 kDa
    Pathways
    Apoptosis, Positive Regulation of Endopeptidase Activity
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