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CD40 antibody (CD40 Molecule, TNF Receptor Superfamily Member 5) Primary Antibody

CD40 Reactivity: Human IHC (fro), FACS Host: Mouse Monoclonal B-B20 unconjugated
Pubmed (4)
Catalog No. ABIN1383854
$354.82
Plus shipping costs $45.00
200 μL
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  • Target
    CD40
    Reactivity
    Human
    • 238
    • 114
    • 45
    • 13
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Host
    Mouse
    • 153
    • 113
    • 50
    • 5
    • 1
    • 1
    Clonality
    Monoclonal
    • 208
    • 112
    • 1
    Conjugate
    This CD40 antibody is un-conjugated
    • 154
    • 30
    • 29
    • 22
    • 13
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    • 187
    • 107
    • 78
    • 64
    • 48
    • 37
    • 27
    • 22
    • 20
    • 13
    • 12
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Specificity
    Recognises the Bp50 antigen, a 48 kDa protein
    Characteristics
    Raji cell line. Carrier and preservative free
    Purification
    Ion exchange chromatography
    Sterility
    0.22 μm filtered
    Clone
    B-B20
    Isotype
    IgG1
  • Application Notes
    Suitable for immunochemistry on frozen section. Suitable for flow cytometry. Stimulates B-cell proliferation together with IL-4.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    200µg/200µl
    Buffer
    Phosphate-buffered saline.
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Declared stable after 7 days at room temperature. Protect from light. Do not freeze.
    Expiry Date
    1 week
  • de Goër de Herve, Durali, Tran, Maigné, Simonetta, Leclerc, Delfraissy, Taoufik: "Differential effect of agonistic anti-CD40 on human mature and immature dendritic cells: the Janus face of anti-CD40." in: Blood, Vol. 106, Issue 8, pp. 2806-14, 2005 (PubMed).

    Durali, de Goër de Herve, Giron-Michel, Azzarone, Delfraissy, Taoufik: "In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment." in: Blood, Vol. 102, Issue 12, pp. 4084-9, 2003 (PubMed).

    Puig-Kröger, Relloso, Fernández-Capetillo, Zubiaga, Silva, Bernabéu, Corbí: "Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells." in: Blood, Vol. 98, Issue 7, pp. 2175-82, 2001 (PubMed).

    Jeannin, Delneste, Lecoanet-Henchoz, Gauchat, Ellis, Bonnefoy: "CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells." in: The Journal of biological chemistry, Vol. 272, Issue 25, pp. 15613-9, 1997 (PubMed).

  • Target
    CD40
    Alternative Name
    CD40 (CD40 Antibody Abstract)
    Synonyms
    Bp50, CDW40, TNFRSF5, p50, AI326936, GP39, HIGM1, IGM, IMD3, T-BAM, TRAP, Tnfrsf5, TNFSF5, CD40 molecule, CD40 antigen, CD40, Cd40
    Background
    Myeloma X63/AG.8653 x Balb/c spleen cells
    Molecular Weight
    48 kDa
    Pathways
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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