PCYT2 antibody (Phosphate Cytidylyltransferase 2, Ethanolamine)

Details for Product anti-PCYT2 Antibody No. ABIN1385871
Antigen
  • ET
  • 1110033E03Rik
  • ethanolamine-phosphate cytidylyltransferase
  • putative ethanolamine-phosphate cytidylyltransferase
  • Ethanolamine-phosphate cytidylyltransferase
  • phosphate cytidylyltransferase 2, ethanolamine
  • phosphate cytidylyltransferase 2, ethanolamine L homeolog
  • Tc00.1047053511727.120
  • Tb11.01.5730
  • LINJ_32_0940
  • LOC5566800
  • LMJF_32_0890
  • EDI_013070
  • EDI_204270
  • CpipJ_CPIJ009320
  • Bm1_01855
  • pcy2
  • PCYT2
  • Pcyt2
  • pcyt2.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
48
37
33
6
5
5
5
5
3
1
1
1
1
1
Host
Rabbit
44
4
Clonality
Polyclonal
Conjugate
This PCYT2 antibody is un-conjugated
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
31
12
8
3
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PCYT2
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PCYT2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Pcyt2 (PCYT2 Antibody Abstract)
Background

Phosphatidylethanolamine (PtdEtn) is a major membrane phospholipid which serves to play a primary role in cell membrane structure and is also involved in cell division, cell signaling, activation, phagocytosis and autophagy. PCYT2 (Phosphorylethanolamine transferase), also known as Ethanolamine-phosphate cytidylyltransferase, is a 389 amino acid protein that catalyzes the formation of CDP-ethanolamine from ethanolamine. This product combined with diacylglycerol form phosphatidylethanolamine via the de novo Kennedy pathway. PCYT2 is expressed at highest levels in heart, liver and skeletal muscle. Elevated levels of MyoD, reduced content of Sp1 and a changed ratio of Sp1 to Sp3 all together stimulate upregulation of PCTY2 transcription during C2C12 muscle cell differentiation. Disruption of the PCYT2 gene in mice leads to death after embryo implantation, establishing the necessity of PCYT2 for murine development.

Synonyms: CTP, phosphoethanolamine cytidylyltransferase, ET, Ethanolamine-phosphate cytidylyltransferase, Ethanolaminephosphate Cytidyltransferase, PCY2, PCY2_HUMAN, Pcyt2, Phosphate cytidylyltransferase 2 ethanolamine, Phosphorylethanolamine transferase.

Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
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