GHRPR/Ghrelin Receptor/GHS-R1 (AA 75-135) antibody

Catalog No. ABIN1386552

Product Details

Target: GHRPR/Ghrelin Receptor/GHS-R1

Binding Specificity: AA 75-135

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ghrelin Receptor

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References

Alves Costa, Pansani, de Castro, Basile Colugnati, Xaxier, Guimarães, Antas Rabelo, Nunes-Souza, Souza Caixeta, Nassar Ferreira: "Milk restriction or oligosaccharide supplementation in calves improves compensatory gain and digestive tract development without changing hormone levels." in: PLoS ONE, Vol. 14, Issue 3, pp. e0214626, (2019) (PubMed).

Target Details

Target: GHRPR/Ghrelin Receptor/GHS-R1

Background:

Synonyms: GH releasing peptide receptor, GH-releasing peptide receptor, Ghrelin receptor, GHRP, GHRPR, GHS-R, GHSR, GHSR_HUMAN, Growth hormone secretagogue receptor 1, Growth hormone secretagogue receptor type 1, growth hormone secretatgogue receptor.

Background: This gene encodes a member of the G-protein coupledreceptor family. The encoded protein may play a role in energyhomeostasis and regulation of body weight. Two identifiedtranscript variants are expressed in several tissues and areevolutionary conserved in fish and swine. One transcript, 1a,excises an intron and encodes the functional protein, this proteinis the receptor for the Ghrelin ligand and defines a neuroendocrinepathway for growth hormone release. The second transcript (1b)retains the intron and does not function as a receptor for Ghrelin,however, it may function to attenuate activity of isoform 1a.Mutations in this gene are associated with autosomal idiopathicshort stature.[provided by RefSeq, Apr 2010].