MMAA antibody (Methylmalonic Aciduria (Cobalamin Deficiency) Type A)

Catalog No. ABIN1387231

Product Details anti-MMAA Antibody

Target:

MMAA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMAA antibody is un-conjugated

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MMAA/cblA

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

Target Details for MMAA

Target:

MMAA

Alternative Name: CblA (MMAA Antibody Abstract)

Synonyms: 2810018E08Rik, AI840684, cblA, methylmalonic aciduria (cobalamin deficiency) type A, methylmalonic aciduria (cobalamin deficiency) cblA type, Mmaa, MMAA

Background:

The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria. [provided by RefSeq, Jul 2008].

Synonyms: mitochondrial, cblA, MMAA protein, Methylmalonic aciduria cobalamin deficiency cblA type, Methylmalonic aciduria cobalamin deficiency type A, Methylmalonic aciduria type A protein, Methylmalonic aciduria type A protein mitochondrial, MMAA, MMAA_HUMAN.

Gene ID: 166785

Pathways: Monocarboxylic Acid Catabolic Process