MMAA antibody

Catalog No. ABIN1387231

Product Details anti-MMAA Antibody

Target: MMAA (Methylmalonic Aciduria (Cobalamin Deficiency) Type A (MMAA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMAA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MMAA/cblA

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MMAA

Target: MMAA (Methylmalonic Aciduria (Cobalamin Deficiency) Type A (MMAA))

Alternative Name: cblA (MMAA Products)

Background:

Synonyms: mitochondrial, cblA, MMAA protein, Methylmalonic aciduria cobalamin deficiency cblA type, Methylmalonic aciduria cobalamin deficiency type A, Methylmalonic aciduria type A protein, Methylmalonic aciduria type A protein mitochondrial, MMAA, MMAA_HUMAN.

Background: The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria. [provided by RefSeq, Jul 2008].

Gene ID: 166785

Pathways: Monocarboxylic Acid Catabolic Process