Olfactory Receptor, Family 10, Subfamily A, Member 5 (OR10A5) antibody

Details for Product No. ABIN1387443
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
21
14
14
Host
Rabbit
21
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
12
7
5
2
2
Options
Immunogen KLH conjugated synthetic peptide derived from human OR10A5
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name Or10a5 (OR10A5 Antibody Abstract)
Background

Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that leads to the perception of smell. While they share a seven transmembrane domain structure with many neurotransmitter and hormone receptors, olfactory receptors are responsible for the recognition and transduction of odorant signals. OR10A2 (olfactory receptor 10A2) and OR10A5 (olfactory receptor 10A5) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family and are encoded by genes that map to human chromosome 11p15.4. Chromosome 11 houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11.

Subcellular location: Extracellular

Synonyms: HP3, O10A5_HUMAN, Olfactory receptor 10A1, Olfactory receptor 10A5, Olfactory receptor 11-403, Olfactory receptor-like protein JCG6, OR10A1, OR10A5, OR11-403, R10A1.

Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months