Trace Amine Associated Receptor 8 (TAAR8) antibody (Biotin)

Details for Product No. ABIN1394713
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
29
15
14
1
1
Host
Rabbit
30
Clonality
Polyclonal
Conjugate
Biotin
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
13
11
9
5
4
Options
Immunogen KLH conjugated synthetic peptide derived from human G protein coupled receptor 102
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name Gpr102/Taar8 (TAAR8 Antibody Abstract)
Background

Trace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TaRs contain several structural features that are similar to the rhodopsin â^-adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder.

Subcellular location: Extracellular

Synonyms: G protein coupled receptor 102, G-protein coupled receptor 102, GPR102, TA5, TAAR8, TAAR8_HUMAN, TaR-5, TaR-8, TAR5, Trace amine assiciated receptor 8, Trace amine receptor 5, Trace amine receptor 8, Trace amine-associated receptor 8, TRAR5, GPCR GPR102.

Application Notes WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months