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EIF4E antibody (Eukaryotic Translation Initiation Factor 4E) AA 121-217 (Alexa Fluor 555) Primary Antibody

EIF4E Reactivity: Human, Rat IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1397206
$476.30
Plus shipping costs $45.00
100 μL
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  • Target See all EIF4E Antibodies
    EIF4E
    Binding Specificity
    • 38
    • 14
    • 11
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-217
    Reactivity
    • 139
    • 66
    • 54
    • 19
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human, Rat
    Host
    • 118
    • 23
    Rabbit
    Clonality
    • 113
    • 28
    Polyclonal
    Conjugate
    • 60
    • 11
    • 9
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This EIF4E antibody is conjugated to Alexa Fluor 555
    Application
    • 89
    • 67
    • 49
    • 35
    • 26
    • 25
    • 20
    • 18
    • 17
    • 11
    • 9
    • 7
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Mouse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human eIF4E
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    EIF4E
    Alternative Name
    eIF4E (EIF4E Products)
    Synonyms
    0260/09, 0587/11, 0589/11, 0919/12, 1004/13, 2, 7238, CBP, CG4035, CT13384, CT39424, CT39426, D-eIF4E, Dmel\\CG4035, Eif4E, Eif4e, IF4E, dEif4e, deIF-4E, deIF4E, eIF 4E, eIF-4E1, eIF-4E2, eIF-4EII, eIF-4e, eIF4E, eIF4E-1, eIF4E-1/2, eIF4E-2, eIF4E1, eIF4EI, eIF4e, eif-4E, eif-4e, eif4e, l(3)07238, l(3)67Af, l(3)S025007, l(3)S026009, l(3)S058711, l(3)S091912, eIF-4E, cbp, eif4f, eif4e1, eif4el1, AUTS19, EIF4E1, EIF4EL1, EIF4F, EG668879, Eif4e-ps, If4e, EIF-4E, eif4e-1, zgc:86680, Eukaryotic initiation factor 4E, eucaryotic initiation factor 6, eukaryotic translation initiation factor 4E, eukaryotic translation initiation factor 4E family member 1B S homeolog, eukaryotic translation initiation factor 4E L homeolog, eukaryotic translation initiation factor 4ea, translation initiation factor eIF4E, eIF-4E, eif6, eif4e, eif4e1b.S, EIF4E, Eif4e, eif4e.L, eif4ea, LOC100533326
    Background

    Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

    Subcellular location: Cytoplasm

    Synonyms: CBP, EIF4F, AUTS19, EIF4E1, EIF4EL1, Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein

    Gene ID
    UniProt
    P06730
    Pathways
    BCR Signaling
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