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Myotilin antibody (MYOT) AA 121-200 (FITC) Primary Antibody

MYOT Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal FITC
Catalog No. ABIN1397530
$476.30
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all Myotilin (MYOT) Antibodies
    Myotilin (MYOT)
    Binding Specificity
    • 14
    • 13
    • 9
    • 8
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    AA 121-200
    Reactivity
    • 53
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 44
    • 7
    • 2
    Rabbit
    Clonality
    • 52
    • 1
    Polyclonal
    Conjugate
    • 20
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Myotilin antibody is conjugated to FITC
    Application
    • 36
    • 29
    • 12
    • 12
    • 10
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Myotilin
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    Myotilin (MYOT)
    Alternative Name
    Myotilin (MYOT Products)
    Synonyms
    LGMD1, LGMD1A, MFM3, TTID, TTOD, 5530402I04Rik, Ttid, MYOT, ttid, myotilin, MYOT, Myot, myot
    Background

    Myotilin, a sarcomeric protein that is encoded by the gene mapping to human chromosome 5q31, binds to a-actinin and is localized in the Z-line of myofibrils. Myotilin is expressed in skeletal and cardiac muscle, and it co-localizes with a-actinin in the sarcomeric I-bands where it directly interacts with a-actinin. Defects in the myotilin gene are reported to cause a form of autosomal dominant limb-girdle muscular dystrophy (LGMD). Symptoms of adult onset LGMD are progressive weakness of the hip and shoulder girdles as well as a distinctive dysarthric pattern of speech. The muscle of affected individuals with LGMD shows degeneration of myofibers, variations in fiber size, fiber splitting, centrally located myonuclei and an enhanced number of autophagic vesicles.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: 57 kDa cytoskeletal protein, LGMD 1, LGMD1, Myofibrillar titin like Ig domains protein, Myofibrillar titin-like Ig domains protein, MYOT, MYOTI_HUMAN, Myotilin, Titin immunoglobulin domain protein, TTID, TTID protein.

    Gene ID
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