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THRAP3 antibody (Thyroid Hormone Receptor Associated Protein 3) AA 631-730 (Alexa Fluor 647) Primary Antibody

THRAP3 Reactivity: Human, Rat IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN1397829
$476.30
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target See all THRAP3 Antibodies
    THRAP3
    Binding Specificity
    • 14
    • 13
    • 10
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 631-730
    Reactivity
    • 54
    • 30
    • 19
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Rat
    Host
    • 55
    Rabbit
    Clonality
    • 55
    Polyclonal
    Conjugate
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This THRAP3 antibody is conjugated to Alexa Fluor 647
    Application
    • 36
    • 20
    • 12
    • 12
    • 7
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Mouse,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Thrap3/TRAP150
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    THRAP3
    Alternative Name
    Thrap3 (THRAP3 Products)
    Synonyms
    TRAP150, 9330151F09Rik, B230333E16Rik, Trap150, trap150, Thrap3, MGC132228, zgc:85716, thyroid hormone receptor associated protein 3, DNA cross-link repair 1A protein, thyroid hormone receptor associated protein 3 S homeolog, thyroid hormone receptor-associated protein 3, thyroid hormone receptor associated protein 3b, THRAP3, CpipJ_CPIJ018886, CpipJ_CPIJ019503, Thrap3, thrap3, thrap3.S, thrap3b
    Background

    In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signaling between transcriptional activators and initiation factors. These complexes include the thyroid hormone receptor-associated protein (TRAP) complex, which interacts with thyroid receptors (TR), vitamin D receptors and other steroid receptors to facilitate hormone induced transcriptional activation. The TRAP complex consists of numerous proteins ranging in size including TRAP95, TRAP100, TRAP150, TRAP220 and TRAP230, that are characterized by the presence of a nuclear receptor recognition motif which mediates the ligand-dependent binding of TRAP proteins to the nuclear receptors. TRAP220 and TRAP100 are widely expressed and most abundantly detected in skeletal muscle, heart and placenta. TRAP95, TRAP150 and TRAP230 facilitate TR induced transcription by associating with an additional transcriptional coactivating complex SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes.

    Subcellular location: Nucleus

    Synonyms: Thrap3, Thyroid hormone receptor associated protein 3, Thyroid hormone receptor-associated protein 3, Thyroid hormone receptor-associated protein complex 150 kDa component, Thyroid hormone receptor-associated protein complex,TR150_HUMAN, Trap150.

    Gene ID
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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