CTDSPL antibody (CTD Small Phosphatase-Like Protein) AA 175-276 (Alexa Fluor 647)

Catalog No. ABIN1398012

Product Details anti-CTDSPL Antibody

Target: CTDSPL

Binding Specificity: AA 175-276

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTDSPL antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Rat,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTDSPL

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Expiry Date: 12 months

Target Details for CTDSPL

Target: CTDSPL

Alternative Name: CTDSPL (CTDSPL Products)

Synonyms: C3orf8, HYA22, PSR1, RBSP3, SCP3, 2810418J22Rik, AI426263, NFI1, NIF, XNIF, ctdspl, ctdspl.L, nif, scp3, CTD small phosphatase like, TIM23 translocase complex subunit Tim50, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, CTD small phosphatase like S homeolog, CTDSPL, SJAG_03560, Ctdspl, ctdspl.S

Background:

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Subcellular location: Nucleus

Synonyms: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, CTD small phosphatase-like protein, CTDSL_HUMAN, CTDSP-like, Ctdspl, hYA22, N-like protein, NLI-interacting factor 1, Nuclear LIM interactor-interacting factor 1, Protein YA22, RBSP3, SCP3, Small C-terminal domain phosphatase 3, Small CTD phosphatase 3.

Gene ID: