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LGI4 antibody (Leucine-Rich Repeat LGI Family, Member 4) AA 101-200 (Alexa Fluor 555) Primary Antibody

LGI4 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1398311
$476.30
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all LGI4 Antibodies
    LGI4
    Binding Specificity
    • 14
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivity
    • 32
    • 15
    • 11
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 30
    • 5
    • 1
    Rabbit
    Clonality
    • 31
    • 5
    Polyclonal
    Conjugate
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGI4 antibody is conjugated to Alexa Fluor 555
    Application
    • 21
    • 12
    • 12
    • 12
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LGI4
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    LGI4
    Alternative Name
    LGI4 (LGI4 Products)
    Synonyms
    Lgil3, clp, LGIL3, leucine rich repeat LGI family member 4, leucine-rich repeat LGI family, member 4, LGI4, Lgi4
    Background

    LGI4, also known as leucine-rich glioma-inactivated protein 4, is a 537 amino acid secreted glycosylated protein that is widely expressed, with highest levels found within the nervous system. Interestingly, siRNA knockdown studies of LGI4 expression in Schwann cells have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation. LGI4 shares significant homology with its other family members, LGI1, LGI2 and LGI3. Significantly, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, given the sequence similarity of LGI4, it is likely that it also may be implicated in the pathology of seizures. LGI4 is localized subcellularly to the Golgi, ER and vesicles. There are two isoforms of LGI4 that are produced as a result of alternative splicing events.

    Subcellular location: Secreted

    Synonyms: Leucine rich glioma inactivated gene 4, Leucine rich glioma inactivated protein 4, leucine-rich repeat LGI family member 4, Leucine rich repeat LGI family member 4, LGI1 like protein 3, LGI4, Lgi4 protein, Lgil3, LGI4_HUMAN.

    Gene ID
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