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FBXW2 antibody (F-Box and WD Repeat Domain Containing 2) AA 321-420 (Alexa Fluor 555) Primary Antibody

FBXW2 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1398827
$476.30
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all FBXW2 Antibodies
    FBXW2
    Binding Specificity
    • 14
    • 10
    • 4
    • 2
    • 1
    AA 321-420
    Reactivity
    • 34
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 26
    • 7
    • 1
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXW2 antibody is conjugated to Alexa Fluor 555
    Application
    • 17
    • 15
    • 12
    • 12
    • 12
    • 3
    • 3
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FbxW2
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    FBXW2
    Alternative Name
    FbxW2 (FBXW2 Products)
    Synonyms
    FBXW2, md6, fbw2, fwd2, MGC53244, FBW2, Fwd2, Md6, wu:fc72f10, zgc:110365, 2700071L08Rik, MD6, F-box and WD repeat domain containing 2, F-box and WD repeat domain containing 2 L homeolog, F-box and WD-40 domain protein 2, FBXW2, fbxw2, Fbxw2, fbxw2.L
    Background

    F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact, F box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins. A large family of mammalian F box proteins has recently been identified and classified into three groups based on the presence of either the WD 40 repeats, the leucine rich repeats, or the presence or absence of other protein protein interacting domains. The FBXW2 gene product, the second identified member of the F box gene family, contains multiple WD 40 repeats.

    Subcellular location: Nucleus

    Synonyms: F box and WD 40 domain containing protein 2, F box and WD repeat domain containing 2, F Box and WD40 Domain Protein 2, F box/WD repeat containing protein 2, FBW 2, FBW2, FBXW 2, Fwd2, Md6, Protein MD6.

    Gene ID
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