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ELL3 antibody (Elongation Factor RNA Polymerase II-Like 3) AA 51-158 (Alexa Fluor 555) Primary Antibody

ELL3 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1399727
$476.30
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all ELL3 Antibodies
    ELL3
    Binding Specificity
    • 14
    • 9
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 51-158
    Reactivity
    • 35
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 2
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ELL3 antibody is conjugated to Alexa Fluor 555
    Application
    • 21
    • 16
    • 12
    • 12
    • 3
    • 3
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ELL3
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    ELL3
    Alternative Name
    ELL3 (ELL3 Products)
    Synonyms
    DKFZp469F0639, A930015D22Rik, elongation factor for RNA polymerase II 3, elongation factor RNA polymerase II-like 3 L homeolog, elongation factor RNA polymerase II-like 3, ELL3, ell3.L, Ell3
    Background

    Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Though similar to ELL and ELL2, ELL3 is exclusively expressed in testis.

    Subcellular location: Nucleus

    Synonyms: B cell translocation gene 2, BTG family member 2, Btg2, BTG2_HUMAN, Nerve growth factor inducible anti prolerative, NGF inducible anti prolerative protein PC3, NGF-inducible anti-prolerative protein PC3, PC3, Pheochromacytoma cell 3, Protein BTG2, TIS21.

    Gene ID
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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