HNRNPU antibody (AA 1-40) (FITC)

Catalog No. ABIN1400792

Product Details anti-HNRNPU Antibody (FITC)

Target: HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))

Binding Specificity: AA 1-40

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPU antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human hnRNP U

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HNRNPU

Target: HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))

Alternative Name: HnRNP U (HNRNPU Products)

Synonyms: AA408410 antibody, AI256620 antibody, AL024194 antibody, AL024437 antibody, AW557595 antibody, C86794 antibody, Hnrpu antibody, SAFA antibody, Sp120 antibody, hnRNP U antibody, SN1 antibody, HNRPU antibody, SAF-A antibody, U21.1 antibody, saf-a antibody, heterogeneous nuclear ribonucleoprotein U antibody, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) S homeolog antibody, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) antibody, Hnrnpu antibody, HNRNPU antibody, hnrnpu.S antibody

Background:

Synonyms: Heterogeneous nuclear ribonucleoprotein U, hnRNP U, hnRNP U protein, HNRNPU, hnRNPU protein, HNRPU, HNRPU_HUMAN, p120, p120 nuclear protein, pp120, SAF A, SAF-A, SAFA, Scaffold attachment factor A, U21.1, GRIP120, C1orf199

Background: Heterogeneous nuclear ribonucleoproteins (hnRNPs) are thought to be involved in pre-mRNA processing. However, its role in the regulation of gene expression is as yet poorly understood. Proteins of the heterogeneous nuclear ribonucleoparticles (hnRNP) family form a structurally diverse group of RNA binding proteins implicated in various functions. Recently, hnRNP proteins have been shown to hinder communication between factors bound to different splice sites. Conversely, several reports have described a positive role for some hnRNP proteins in pre-mRNA splicing. hnRNP-U, also termed scaffold attachment factor A (SAF-A), binds to pre-mRNA and nuclear matrix/scaffold attachment region DNA elements.

Gene ID: 3192

UniProt: Q00839