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VGLL4 antibody (Vestigial Like 4) AA 220-270 (Alexa Fluor 555) Primary Antibody

VGLL4 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1401329
$476.30
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target See all VGLL4 Antibodies
    VGLL4
    Binding Specificity
    • 16
    • 14
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    AA 220-270
    Reactivity
    • 42
    • 19
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 41
    • 1
    Rabbit
    Clonality
    • 42
    Polyclonal
    Conjugate
    • 14
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VGLL4 antibody is conjugated to Alexa Fluor 555
    Application
    • 26
    • 22
    • 12
    • 3
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human VGLL4
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    VGLL4
    Alternative Name
    VGLL4 (VGLL4 Products)
    Synonyms
    DKFZp459C0333, VGL-4, BC048841, vestigial-like family member 4, vestigial like family member 4, Vgll4, VGLL4
    Background

    The transcriptional enhancer factor-1 (TEF-1) family of transcription factors regulate tissue-specific gene expression in muscle and placenta. The mechanism whereby TEF-1 confers tissue specificity depends largely on the interaction of TEF-1 with tissue-specific cofactors. Transcription cofactor Vgl-4 (vestigial-like protein 4) is a 290 amino acid nuclear protein that interacts with TEF-1 and MEF-2. Vgl-4 is the only member of the vestigial-like family that is expressed in heart. Overexpression of Vgl-4 in cardiac myocytes interferes with basal expression and ?-adrenergic receptor-dependent activation of a TEF-1 dependent skeletal ?actin promoter. This suggests that Vgl-4 counteracts ?-adrenergic activation of gene expression in cardiomyocytes. There are two isoforms of Vgl-4 that are produced as a result of alternative splicing events.

    Synonyms: Transcription cofactor vestigial like protein 4, Vestigial like protein 4, VGL 4, VGLL4, VGLL4_HUMAN.

    Gene ID
    UniProt
    Q14135
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