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CST5 antibody (Cystatin D) (Biotin) Primary Antibody

CST5 Reactivity: Human IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1401511
$453.20
Plus shipping costs $45.00
100 μL
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  • Target See all CST5 Antibodies
    CST5
    Reactivity
    • 24
    • 4
    Human
    Host
    • 21
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 24
    • 2
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CST5 antibody is conjugated to Biotin
    Application
    • 13
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Cystatin D
    Isotype
    IgG
  • Application Notes
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    CST5
    Alternative Name
    Cystatin D (CST5 Products)
    Synonyms
    Cst10, Cystatin-5, cystatin D, CST5, Cst5
    Background

    The cystatin superfamily is a well-established family of cysteine protease inhibitors. Cystatins A and B (type 1) are mainly intracellular, cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2), and the kininogens are type 3 cystatins which are intravascular proteins. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes. Cystatin SA, cystatin S and cystatin SN are found primarily in saliva. Cystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins. The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation. High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.

    Synonyms: CST 5, CST5, Cystatin 5, Cystatin5, Cystatin-5, CystatinD, Cystatin D, Cysteine proteinase inhibitor, MGC71922, CYTD_HUMAN.

    Gene ID
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