ZC2HC1C antibody (AbBy Fluor® 647)

Catalog No. ABIN1403658

Product Details anti-ZC2HC1C Antibody (AbBy Fluor® 647)

Target: ZC2HC1C (Zinc Finger, C2HC-Type Containing 1C (ZC2HC1C))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC2HC1C antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C14ORF140/FAM164C

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZC2HC1C

Target: ZC2HC1C (Zinc Finger, C2HC-Type Containing 1C (ZC2HC1C))

Alternative Name: C14ORF140 (ZC2HC1C Products)

Synonyms: C14orf140 antibody, FAM164C antibody, 2810002I04Rik antibody, AV046379 antibody, Fam164c antibody, RGD1307122 antibody, zinc finger C2HC-type containing 1C antibody, zinc finger, C2HC-type containing 1C antibody, ZC2HC1C antibody, Zc2hc1c antibody

Background:

Synonyms: chromosome 14 open reading frame 140, FAM164C, family with sequence similarity 164 member C, FLJ23093, UPF0418 protein FAM164C, ZC21C_HUMAN.

Background: Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5 % of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14,19) translocations found in a variety of B cell malignancies. The C14orf140 gene product has been provisionally designated C14orf140 pending further characterization.