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C14orf174 antibody (AbBy Fluor® 488)

C14orf174 Reactivity: Human, Rat, Mouse WB, IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN1403674
  • Target See all C14orf174 products
    C14orf174 (Chromosome 14 Open Reading Frame 174 (C14orf174))
    Reactivity
    • 21
    • 14
    • 14
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C14orf174 antibody is conjugated to AbBy Fluor® 488
    Application
    • 18
    • 12
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SAMD15/C14orf174
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    C14orf174 (Chromosome 14 Open Reading Frame 174 (C14orf174))
    Alternative Name
    C14orf174 (C14orf174 Products)
    Synonyms
    C14orf174 antibody, FAM15A antibody, Gm263 antibody, sterile alpha motif domain containing 15 antibody, SAMD15 antibody, Samd15 antibody
    Background

    Synonyms: chromosome 14 open reading frame 174, FAM15A, SAM domain-containing protein 15, SAM15_HUMAN, SAMD15, Sterile alpha mot domain-containing protein 15.

    Background: C14orf174, is a 674 amino acid protein that contains one SAM (sterile alpha motif) domain. Existing as two alternatively spliced isoforms,C14orf174 is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5 % of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the (14,19) translocations found in a variety of B cell malignancies.

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