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IL7R antibody (Interleukin 7 Receptor) Primary Antibody

IL7R Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1513091
$589.88
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  • Target
    IL7R
    Reactivity
    • 103
    • 72
    • 15
    • 7
    • 5
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 89
    • 29
    • 24
    • 7
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 93
    • 61
    Polyclonal
    Conjugate
    • 65
    • 12
    • 11
    • 10
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL7R antibody is un-conjugated
    Application
    • 74
    • 57
    • 54
    • 26
    • 16
    • 13
    • 9
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human IL7R
    Isotype
    IgG
  • Application Notes
    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C/-80 °C
  • Target
    IL7R
    Alternative Name
    IL7R (IL7R Antibody Abstract)
    Synonyms
    IL7R, CD127, IL-7Ralpha, CDW127, IL-7R-alpha, IL7RA, ILRA, IL-7RA, interleukin 7 receptor, IL7R, Il7r
    Background
    The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
    Synonyms: IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
    Gene ID
    3575
    UniProt
    P16871
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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