This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PPP1R3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human PPP1R3B.
The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA, MIM 176875) is regulated by targeting subunits, such as PP1R3B. PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e., inactivates) glycogen phosphorylase (see PYGL, MIM 232700) and enhances the rate at which it activates glycogen synthase (see GYS2, MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[supplied by OMIM].