PPP1R3B antibody (Regulatory Subunit 3B)

Catalog No. ABIN7165933

Product Details anti-PPP1R3B Antibody

Target: PPP1R3B (Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B))

Binding Specificity: AA 1-285, Regulatory Subunit 3B

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R3B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein phosphatase 1 regulatory subunit 3B protein (1-285AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP1R3B

Target: PPP1R3B (Protein Phosphatase 1, Regulatory Subunit 3B (PPP1R3B))

Alternative Name: PPP1R3B (PPP1R3B Products)

Synonyms: 6430576E21 antibody, AW821953 antibody, GL antibody, PTG antibody, PPP1R4 antibody, wu:fd20c10 antibody, wu:fi66d07 antibody, zgc:55542 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 3B antibody, protein phosphatase 1, regulatory subunit 3B antibody, protein phosphatase 1 regulatory subunit 3B antibody, protein phosphatase 1 regulatory subunit 3B L homeolog antibody, protein phosphatase 1 regulatory subunit 3B S homeolog antibody, Ppp1r3b antibody, PPP1R3B antibody, ppp1r3b.L antibody, ppp1r3b.S antibody, ppp1r3b antibody

Background:

Background: Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes.

Aliases: FLJ14005 antibody, FLJ34675 antibody, GL antibody, Hepatic glycogen targeting protein phosphatase 1 regulatory subunit GL antibody, Hepatic glycogen targeting subunit G(L) antibody, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL antibody, PP1 subunit R4 antibody, Ppp1r3b antibody, PPP1R4 antibody, PPR3B_HUMAN antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 3B antibody, Protein phosphatase 1 regulatory subunit 3B antibody, Protein phosphatase 1 regulatory subunit 4 antibody, Protein phosphatase 1 subunit 4 antibody, Protein phosphatase 1 subunit GL antibody, PTG antibody, R4 antibody

UniProt: Q86XI6

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process