LIMS2 antibody (AA 251-341) (AbBy Fluor® 555)
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- Target See all LIMS2 Antibodies
- LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))
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Binding Specificity
- AA 251-341
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LIMS2 antibody is conjugated to AbBy Fluor® 555
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LIMS2
- Isotype
- IgG
- Top Product
- Discover our top product LIMS2 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LIMS2 (LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2))
- Alternative Name
- LIMS2 (LIMS2 Products)
- Synonyms
- PINCH2 antibody, PINCH-2 antibody, LIMS1 antibody, LIM and senescent cell antigen like domains 2 antibody, LIM zinc finger domain containing 2 antibody, Lims2 antibody, LIMS2 antibody
- Background
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Synonyms: FLJ10044, ILK binding protein, LIM and senescent cell antigen like domains 2, LIM and senescent cell antigen-like-containing domain protein 2, LIM-like protein 2, LIMS2, LIMS2_HUMAN, Particularly interesting new Cys-His protein 2, PINCH 2, PINCH-2, PINCH2.
Background: Pinch is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cytoplasmic protein expressed in most tissues and consists of five LIM domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by another member of the Pinch family, PINCH-2, which also forms a complex with ILK.
- Pathways
- Cell-Cell Junction Organization
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