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STRA6 antibody (Stimulated By Retinoic Acid 6) (Cy5) Primary Antibody

STRA6 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN1704601
$442.20
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target
    STRA6
    Reactivity
    Human, Mouse, Rat
    • 40
    • 38
    • 17
    • 5
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This STRA6 antibody is conjugated to Cy5
    • 18
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • 40
    • 34
    • 12
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human STRA6
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4°C
    Expiry Date
    12 months
  • Target
    STRA6
    Alternative Name
    Stra6 (STRA6 Antibody Abstract)
    Synonyms
    MCOPCB8, MCOPS9, AI891933, RGD1307551, STRA6, im:7151282, wu:fc51h06, zgc:136689, mcops9, pp14296, stimulated by retinoic acid 6, stimulated by retinoic acid gene 6, stimulated by retinoic acid gene 6 homolog (mouse), STRA6, Stra6, stra6
    Background

    STRA6 is a 667 amino acid, multi-pass cell membrane protein. Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Ultimately increasing cellular retinol uptake from the retinol-RBP complex, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, where it is metabolized. Stra6 is broadly expressed, with 4 named isoforms that exist as a result of alternative splicing events. Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, also known as Spear Syndrome. This syndrome is characterized by anophtalmia, mild facial dysmorphism and malformations of the heart, lung and diaphragm. The Stra6 gene maps to chromosome 15q24.1.

    Subcellular location: Extracellular

    Synonyms: Stimulated by retinoic acid gene 6 protein homolog, STRA6_HUMAN.

    Gene ID
    64220
    Pathways
    Feeding Behaviour
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