STRA6 antibody (Stimulated By Retinoic Acid 6) (Cy5)

Details for Product anti-STRA6 Antibody No. ABIN1704601
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
54
40
19
5
1
Host
Rabbit
64
8
2
Clonality
Polyclonal
Conjugate
This STRA6 antibody is conjugated to Cy5
8
7
5
3
3
3
2
2
2
2
2
2
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
47
39
12
9
6
3
2
1
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human STRA6
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name Stra6 (STRA6 Antibody Abstract)
Background

STRA6 is a 667 amino acid, multi-pass cell membrane protein. Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Ultimately increasing cellular retinol uptake from the retinol-RBP complex, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, where it is metabolized. Stra6 is broadly expressed, with 4 named isoforms that exist as a result of alternative splicing events. Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, also known as Spear Syndrome. This syndrome is characterized by anophtalmia, mild facial dysmorphism and malformations of the heart, lung and diaphragm. The Stra6 gene maps to chromosome 15q24.1.

Subcellular location: Extracellular

Synonyms: Stimulated by retinoic acid gene 6 protein homolog, STRA6_HUMAN.

Gene ID 64220
Pathways Feeding Behaviour
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months