S100A6 antibody (S100 Calcium Binding Protein A6) (Cy5)

Details for Product anti-S100A6 Antibody No. ABIN1704757
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
112
56
44
12
2
2
1
1
1
Host
Rabbit
99
32
9
3
2
1
Clonality
Polyclonal
Conjugate
This S100A6 antibody is conjugated to Cy5
18
12
4
2
2
2
2
2
2
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
114
70
53
20
18
12
11
9
7
5
5
4
1
Options
Immunogen KLH conjugated synthetic peptide derived from human S100A6
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name S100A6 (S100A6 Antibody Abstract)
Background

Calcyclin, also known as Protein S100-A6, growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.

Synonyms: S100 alpha 6 PRA, Calcyclin, PRAGrowth factor inducible protein 2A9, Prolactin receptor associated protein, Prolactin receptor-associated protein, Protein S100 A6, Protein S100-A6, S100 A6, S100 calcium binding protein A6 calcyclin, S100 calcium binding protein A6, S100 calcium-binding protein A6, S100A6, S100A6_HUMAN, S100-A6, 2A9, 5B10, CABP, CACY, Calcyclin, Growth factor inducible protein 2A9, Growth factor-inducible protein 2A9, MLN 4, MLN4.

Gene ID 10014
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months