S100A6 antibody

Catalog No. ABIN969470

There are 2+ publications for this product available. The Mouse Monoclonal anti-S100A6 antibody is suitable to detect S100A6 in samples from Human. It has been validated for IHC and ELISA.

Quick Overview for S100A6 antibody (ABIN969470)

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A6 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 7D11

Product Details anti-S100A6 Antibody

Purpose: S100A6 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of calcyclin expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-S100A6 antibody (ABIN969470)

Bean, Salamon, Raffaello, Campanaro, Pallavicini, Lanfranchi: "The Ankrd2, Cdkn1c and calcyclin genes are under the control of MyoD during myogenic differentiation." in: Journal of molecular biology, Vol. 349, Issue 2, pp. 349-66, (2005) (PubMed).

Hwang, Lee, Kim, Li, Jin, Rhee, Kim, Lim: "Calcyclin, a Ca2+ ion-binding protein, contributes to the anabolic effects of simvastatin on bone." in: The Journal of biological chemistry, Vol. 279, Issue 20, pp. 21239-47, (2004) (PubMed).

Target Details for S100A6

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Alternative Name: S100A6

Background: Calcyclin encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Gene ID: 6277

UniProt: P06703

Pathways: S100 Proteins