GK2 antibody (Glycerol Kinase 2) (Cy5)

Details for Product anti-GK2 Antibody No. ABIN1704926
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
81
19
18
3
2
2
2
1
1
Host
Rabbit
74
7
Clonality
Polyclonal
Conjugate
This GK2 antibody is conjugated to Cy5
5
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
61
33
24
12
11
10
6
4
3
1
1
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human GK2/Glycerol kinase 2
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name Gk2/Glycerol Kinase 2 (GK2 Antibody Abstract)
Background

GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Synonyms: ATP:glycerol 3 phosphotransferase, EC 2.7.1.30, GK 2, GK, GKP2, GKTA, Glycerokinase, Glycerol kinase 2, Glycerol kinase testis specic 2, GLPK2_HUMAN.

Gene ID 2712
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months