FAM221A antibody (AA 201-298) (HRP)

Catalog No. ABIN1710951

Product Details anti-FAM221A Antibody (HRP)

Target: FAM221A (Family with Sequence Similarity 221, Member A (FAM221A))

Binding Specificity: AA 201-298

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM221A antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C7orf46

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM221A

Target: FAM221A (Family with Sequence Similarity 221, Member A (FAM221A))

Alternative Name: C7orf46 (FAM221A Products)

Synonyms: C7orf46 antibody, D330028D13Rik antibody, c7orf46 antibody, family with sequence similarity 221 member A antibody, family with sequence similarity 221, member A antibody, family with sequence similarity 221 member A L homeolog antibody, FAM221A antibody, Fam221a antibody, fam221a.L antibody

Background:

Synonyms: C7orf46, F221A_HUMAN, Chromosome 7 open reading frame 46, Uncharacterized protein C7orf46.

Background: Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf46 gene product has been provisionally designated C7orf46 pending further characterization.