MPP4 antibody (AA 331-430) (HRP)

Catalog No. ABIN1711610

Product Details anti-MPP4 Antibody (HRP)

Target: MPP4 (Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) (MPP4))

Binding Specificity: AA 331-430

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPP4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MPP4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MPP4

Target: MPP4 (Membrane Protein, Palmitoylated 4 (MAGUK P55 Subfamily Member 4) (MPP4))

Alternative Name: MPP4 (MPP4 Products)

Background:

Synonyms: MAGUK p55 subfamily member 4, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein, Discs large homolog 6, MPP4_HUMAN, ALS2CR5, DLG6, DLG6, Membrane palmitoylated protein 4, Membrane protein, palmitoylated 4 MAGUK p55 subfamily member 4, OTTHUMP00000205933, OTTHUMP00000209441, OTTHUMP00000209442, OTTHUMP00000209443.

Background: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

Gene ID: 58538

Pathways: Synaptic Membrane