Decorin antibody (DCN) (AA 263-324)

Details for Product anti-DCN Antibody No. ABIN1724878
Antigen
Epitope
AA 263-324
16
15
8
7
6
5
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
145
60
45
11
10
9
7
5
5
3
3
3
3
2
2
2
Host
Mouse
112
27
11
7
2
Clonality (Clone)
Monoclonal ()
Conjugate
This Decorin antibody is un-conjugated
14
8
7
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
115
67
41
18
8
7
6
5
5
4
2
2
2
1
Options
Immunogen Purified recombinant fragment of human DCN (AA 263-324) expressed in E. Coli.
Clone 1G4C5
Isotype IgG1
Purification Purified
Antigen
Alternative Name DCN (DCN Antibody Abstract)
Background The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. ,
Molecular Weight 39.7 kDa
Gene ID 1634
HGNC 1634
Pathways Glycosaminoglycan Metabolic Process
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Decorin (DCN) (AA 263-324) antibody (ABIN1724878) anti-Decorin (DCN) (AA 263-324) antibody (Image 1)
Image no. 2 for anti-Decorin (DCN) (AA 263-324) antibody (ABIN1724878) anti-Decorin (DCN) (AA 263-324) antibody (Image 2)
Image no. 3 for anti-Decorin (DCN) (AA 263-324) antibody (ABIN1724878) anti-Decorin (DCN) (AA 263-324) antibody (Image 3)
Product cited in: Buraschi, Neill, Owens, Iniguez, Purkins, Vadigepalli, Evans, Schaefer, Peiper, Wang, Iozzo: "Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model." in: PLoS ONE, Vol. 7, Issue 9, pp. e45559, 2012 (PubMed).

Adam, Saller, Ströbl, Hennebold, Dissen, Ojeda, Stouffer, Berg, Berg, Mayerhofer: "Decorin is a part of the ovarian extracellular matrix in primates and may act as a signaling molecule." in: Human reproduction (Oxford, England), Vol. 27, Issue 11, pp. 3249-58, 2012 (PubMed).