serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody

Details for Product No. ABIN1724894, Supplier: Log in to see
Antigen
  • C730040N12Rik
  • Tbg
  • TBG
  • THYROXINE-BINDING GLOBULIN
  • serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
  • serpin family A member 7
  • Serpina7
  • SERPINA7
Alternatives
anti-Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 antibody for Immunodiffusion
Epitope
AA 168-302
9
6
5
5
5
5
4
4
3
3
2
2
1
1
1
Reactivity
Human
106
13
9
1
1
Host
Mouse
72
39
5
3
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
8
7
3
3
2
2
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
63
47
39
14
12
11
10
9
9
7
3
3
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of human SERPINA7 (AA 168-302) expressed in E. Coli.
Clone 5B11E9
Isotype IgG1
Purification Purified
Antigen
Alternative Name SERPINA7 (SERPINA7 Antibody Abstract)
Background There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. ,
Molecular Weight 46.3 kDa
Gene ID 6906
HGNC 6906
Pathways Hormone Transport
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
ELISA image for anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (ABIN1724894) anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody
Flow Cytometry (FACS) image for anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (ABIN1724894) anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (Image 2)
Immunocytochemistry (ICC) image for anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (ABIN1724894) anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (Image 3)
Western Blotting (WB) image for anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (ABIN1724894) anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (Image 4)
Western Blotting (WB) image for anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (ABIN1724894) anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (Image 5)
Immunohistochemistry (IHC) image for anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (ABIN1724894) Immunohistochemical analysis of paraffin-embedded liver cancer tissues using SERPINA7...
Immunohistochemistry (IHC) image for anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 7 (SERPINA7) (AA 168-302) antibody (ABIN1724894) Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using SERPIN...
Product cited in: Yan, Yan, Ou: "Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern." in: Gene, Vol. 506, Issue 2, pp. 289-94, 2012 (PubMed).

Duhan, Patston: "Explanation for the high heat stability of thyroxine binding globulin-Chicago." in: Endocrine regulations, Vol. 44, Issue 2, pp. 43-7, 2010 (PubMed).

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