PAPLN antibody (Papilin, Proteoglycan-Like Sulfated Glycoprotein) (AA 766-870)

Details for Product anti-PAPLN Antibody No. ABIN1724895
Antigen
Epitope
AA 766-870
7
4
2
1
1
Reactivity
Human
15
2
2
2
2
1
1
1
Host
Mouse
8
7
Clonality (Clone)
Monoclonal ()
Conjugate
This PAPLN antibody is un-conjugated
1
1
1
Application
ELISA, Western Blotting (WB)
10
10
1
1
1
1
Options
Immunogen Purified recombinant fragment of human PAPLN (AA 766-870) expressed in E. Coli.
Clone 5F2D10
Isotype IgG1
Purification Purified
Antigen
Alternative Name PAPLN
Background Papilin is an extracellular matrix glycoprotein involved in, thin matrix layers during gastrulation, matrix associated with wandering, phagocytic hemocytes, basement membranes and space-filling matrix during Drosophila development.Determination of its cDNA sequence led to the identification of Caenorhabditis and mammalian papilins. A distinctly conserved 'papilin cassette' of domains at the amino-end of papilins is also the carboxyl-end of the ADAMTS subgroup of secreted, matrix-associated metalloproteinases, this cassette contains one thrombospondin type 1 (TSR) domain, a specific cysteine-rich domain and several partial TSR domains. In vitro, papilin non-competitively inhibits procollagen N-proteinase, an ADAMTS metalloproteinase. ,
Molecular Weight 137.7 kDa
Gene ID 89932
HGNC 89932
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN) (AA 766-870) antibody (ABIN1724895) anti-Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN) (AA 766-870) antibody (Image 1)
Image no. 2 for anti-Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN) (AA 766-870) antibody (ABIN1724895) anti-Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN) (AA 766-870) antibody (Image 2)
Image no. 3 for anti-Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN) (AA 766-870) antibody (ABIN1724895) anti-Papilin, Proteoglycan-Like Sulfated Glycoprotein (PAPLN) (AA 766-870) antibody (Image 3)
Product cited in: Fessler, Kramerova, Kramerov, Chen, Fessler: "Papilin, a novel component of basement membranes, in relation to ADAMTS metalloproteases and ECM development." in: The international journal of biochemistry & cell biology, Vol. 36, Issue 6, pp. 1079-84, 2004 (PubMed).

Kramerova, Kawaguchi, Fessler, Nelson, Chen, Kramerov, Kusche-Gullberg, Kramer, Ackley, Sieron, Prockop, Fessler: "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases." in: Development (Cambridge, England), Vol. 127, Issue 24, pp. 5475-85, 2001 (PubMed).