ACE2 antibody (Angiotensin I Converting Enzyme 2) (Internal Region)

Details for Product anti-ACE2 Antibody No. ABIN1731442
Antigen
Epitope
Internal Region
27
26
17
16
15
11
11
10
9
9
9
7
6
5
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
293
74
51
19
2
2
2
2
1
1
Host
Rabbit
254
55
4
Clonality
Polyclonal
Conjugate
This ACE2 antibody is un-conjugated
30
14
10
9
9
8
3
3
3
3
3
3
3
2
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
264
153
116
61
51
13
13
10
7
6
4
4
3
1
1
Options
Immunogen Synthetic peptide from human ACE2.
Isotype IgG
Specificity Reacts with human ACE2 (internal part)
Cross-Reactivity Mouse (Murine)
Cross-Reactivity (Details) Cross reacts with mouse ACE2 protein.
Purification Antigen affinity purified
Antigen
Alternative Name ACE-2 (ACE2 Antibody Abstract)
Background Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
UniProt Q9BYF1
Pathways ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Application Notes

Working dilution: IHC - P (2.5 μg/mL), WB (0.5 - 2 μg/mL)

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, Sodium azide 0.02 %
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Supplier Images
Image no. 1 for anti-Angiotensin I Converting Enzyme 2 (ACE2) (Internal Region) antibody (ABIN1731442) anti-Angiotensin I Converting Enzyme 2 (ACE2) (Internal Region) antibody