ANAPC4 antibody (Anaphase Promoting Complex Subunit 4) N-Term

Catalog No. ABIN1731762

Product Details anti-ANAPC4 Antibody

Target: ANAPC4

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)

Specificity: Reacts with human ANAPC4

Purification: Antigen affinity purified

Immunogen: 14 amino acid peptide near the amino terminus of human APC4.

Isotype: IgG

Application Details

Application Notes:

Working dilution: ELISA, IHC - P (5 μg/mL), WB (1 - 2 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.02 %

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.

Target Details for ANAPC4

Target: ANAPC4

Alternative Name: ANAPC4 / APC4 (ANAPC4 Products)

Synonyms: MGC81278, DDBDRAFT_0186409, DDBDRAFT_0234268, DDB_0186409, DDB_0234268, APC4, ANAPC4, 2610306D21Rik, D5Ertd249e, F18E5.150, F18E5_150, anaphase promoting complex subunit 4, anaphase promoting complex subunit 4 L homeolog, Transducin/WD40 repeat-like superfamily protein, Anapc4, anapc4.L, ANAPC4, anapc4, APC4

Background: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

UniProt: Q9UJX5

Pathways: M Phase