GOSR2 antibody (Cytoplasmic Domain)

Catalog No. ABIN1742357

Product Details anti-GOSR2 Antibody

Target: GOSR2 (Golgi SNAP Receptor Complex Member 2 (GOSR2))

Binding Specificity: AA 2-190, Cytoplasmic Domain

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GOSR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: Specific for membrin.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Recombinant cytoplasmic domain of rat membrin (aa 2-190).

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: 1 : 100 up to 1 : 1000
IHC: not tested yet

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-GOSR2 antibody (ABIN1742357)

Kudlyk, Willett, Pokrovskaya, Lupashin: "COG6 interacts with a subset of the Golgi SNAREs and is important for the Golgi complex integrity." in: Traffic (Copenhagen, Denmark), Vol. 14, Issue 2, pp. 194-204, (2013) (PubMed).

Target Details for GOSR2

Target: GOSR2 (Golgi SNAP Receptor Complex Member 2 (GOSR2))

Alternative Name: Membrin (GOSR2 Products)

Background: Synonyms: GOSR 2, GS 27, GOS 27

Pathways: ER-Nucleus Signaling