EIF2S2 antibody (C-Term)

Catalog No. ABIN1881289

Product Details anti-EIF2S2 Antibody

Target: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Binding Specificity: AA 270-299, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2S2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, M, Rb

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EIF2S2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the C-terminal region of human EIF2S2.

Clone: RB42764

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-EIF2S2 antibody (ABIN1881289)

Rajesh, Iyer, Suragani, Ramaiah: "Intersubunit and interprotein interactions of alpha- and beta-subunits of human eIF2: Effect of phosphorylation." in: Biochemical and biophysical research communications, Vol. 374, Issue 2, pp. 336-40, (2008) (PubMed).

Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, (2007) (PubMed).

Mikami, Masutani, Sonenberg, Yokoyama, Imataka: "An efficient mammalian cell-free translation system supplemented with translation factors." in: Protein expression and purification, Vol. 46, Issue 2, pp. 348-57, (2006) (PubMed).

Target Details for EIF2S2

Target: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Alternative Name: EIF2S2 (EIF2S2 Products)

Background: Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.

Molecular Weight: 38388

NCBI Accession: NP_003899

UniProt: P20042