CD51 antibody (Cleaved-Lys889)
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- Target See all CD51 (ITGAV) Antibodies
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Binding Specificity
- Cleaved-Lys889
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD51 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Isotype
- IgG1
- Top Product
- Discover our top product ITGAV Primary Antibody
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Storage
- 4 °C,-20 °C
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Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51." in: Cytogenetics and cell genetics, Vol. 89, Issue 3-4, pp. 268-71, (2000) (PubMed).
: "Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs." in: The Journal of biological chemistry, Vol. 262, Issue 29, pp. 14080-5, (1987) (PubMed).
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Cloning and characterisation of ITGAV, the genomic sequence for human cell adhesion protein (vitronectin) receptor alpha subunit, CD51." in: Cytogenetics and cell genetics, Vol. 89, Issue 3-4, pp. 268-71, (2000) (PubMed).
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- Target
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Alternative Name
- ITGAV (ITGAV Products)
- Background
- The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
- Molecular Weight
- 116038 Da
- Gene ID
- 3685
- UniProt
- P06756
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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