Toxin of epsilon-zeta Postsegregational Killing System (ZETA) antibody (Biotin)

Details for Product No. ABIN1994325
Antigen
Reactivity
Streptococcus agalactiae
7
Host
Rabbit
7
Clonality
Polyclonal
Conjugate
Biotin
2
2
1
Application
ELISA, Western Blotting (WB)
7
3
Options
Immunogen Recombinant Streptococcus agalactiae Toxin zeta protein
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation
Antigen
Alternative Name Toxin zeta (ZETA Antibody Abstract)
Background Toxic component of a toxin-antitoxin (TA) module. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3\'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Phosphorylation is inhibited by cognate epsilon antitoxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. The zeta toxin induces programmed cell death
Synonyms: UDP-N-acetylglucosamine kinase, UNAG kinase
UniProt P0A4M2
Application Notes Optimal working concentration should be determinde by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4
Preservative ProClin
Precaution of Use This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freeze.
Storage -20 °C/-80 °C
Storage Comment Upon delivery aliquot and store at -20 °C or -80 °C.