DR3/LARD antibody (AA 25-40)

Catalog No. ABIN205831

Product Details anti-DR3/LARD Antibody

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Binding Specificity: AA 25-40

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR3/LARD antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Recognizes a 59kD apoptosis related protein designated DR3 (death receptor-3). DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95). The ligand for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-KB activation.

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Gorilla, Monkey (94%) Gibbon (88%).

Purification: Purified

Immunogen: Peptide sequence QGGTRSPRCDCAGDFH from amino terminus of human DR3 ( N-TERMINAL ). Percent identity by BLAST analysis: Human (100%), Gorilla, Monkey (94%), Gibbon (88%).

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:500 - 1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Alternative Name: TNFRSF25 / DR3 (TNFRSF25 Products)

Background: Name/Gene ID: TNFRSF25
Family: TNF Receptor

Synonyms: TNFRSF25, APO-3, APO3, DDR3, Death receptor 3, DR3, Death receptor beta, LARD, Protein WSL, TR3, WSL, WSL-1, WSL-LR, Apoptosis inducing receptor, TNFRSF12, WSL1, Protein WSL-1, TRAMP

Gene ID: 8718

UniProt: Q93038

Pathways: Apoptosis