PTGER2 antibody (Cytoplasmic Domain)

Catalog No. ABIN213470

Product Details anti-PTGER2 Antibody

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Binding Specificity: Cytoplasmic Domain

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGER2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human EP2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PTGER4 (50 % ).

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Elephant (94%) Rat, Sheep, Bovine, Horse (88%) Dog, Hamster, Panda (81%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 16 amino acid peptide from 2nd cytoplasmic domain of human EP2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Elephant (94%), Rat, Sheep, Bovine, Horse (88%), Dog, Hamster, Panda (81%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P (10 - 20 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20-40 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PTGER2

Target: PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))

Alternative Name: PTGER2 / EP2 (PTGER2 Products)

Background: Name/Gene ID: PTGER2
Subfamily: Prostanoid
Family: GPCR

Synonyms: PTGER2, EP2 prostaglandin e2 receptor, EP2 prostaglandin receptor, EP2, Pge2-r ep2, PGE2 receptor EP2 subtype, Prostaglandin E receptor 2, Prostanoid EP2 receptor, EP2 receptor, PGE receptor EP2 subtype

Gene ID: 5732