RAD54L2 antibody (RAD54-Like 2 (S. Cerevisiae))

Catalog No. ABIN2422109

Product Details anti-RAD54L2 Antibody

Target:

RAD54L2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD54L2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Antigen affinity purification

Immunogen: Recombinant protein of human RAD54L2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C (regular) and -80°C (long term).

Target Details for RAD54L2

Target:

RAD54L2

Alternative Name: RAD54L2 (RAD54L2 Antibody Abstract)

Synonyms: Arip4, D130058C05, G630026H09Rik, Srisnf2l, ARIP4, HSPC325, SRISNF2L, RAD54 like 2 (S. cerevisiae), RAD54 like 2, Rad54l2, RAD54L2

Background: Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.
Synonyms: ARIP4, HSPC325, SRISNF2L