YARS2 antibody

Catalog No. ABIN2422815

Product Details anti-YARS2 Antibody

Target: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human YARS2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for YARS2

Target: YARS2 (Tyrosyl-tRNA Synthetase 2, Mitochondrial (YARS2))

Alternative Name: YARS2 (YARS2 Products)

Synonyms: 2210023C10Rik antibody, tyrRS antibody, CGI-04 antibody, RGD1311696 antibody, MLASA2 antibody, MT-TYRRS antibody, TYRRS antibody, tyrosyl-tRNA synthetase 2 (mitochondrial) antibody, tyrosyl-tRNA synthetase 2 antibody, Yars2 antibody, YARS2 antibody

Background: This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).