SETD2 antibody
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- Target See all SETD2 Antibodies
- SETD2 (SET Domain Containing 2 (SETD2))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SETD2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human SETD2
- Isotype
- IgG
- Top Product
- Discover our top product SETD2 Primary Antibody
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- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Handling Advice
- Avoid freeze / thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SETD2 (SET Domain Containing 2 (SETD2))
- Alternative Name
- SETD2 (SETD2 Products)
- Background
- Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
- Pathways
- Tube Formation
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