Potassium Voltage-Gated Channel, Delayed-Rectifier, Subfamily S, Member 1 (KCNS1) antibody

Details for Product No. ABIN2458130
Target
Reactivity
Human
15
10
10
1
1
1
1
1
1
Host
Rabbit
15
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
10
3
2
1
Options
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNS1.
Purification Antibody is purified by peptide affinity chromatography method.
Target
Alternative Name KCNS1 (KCNS1 Antibody Abstract)
Background Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. KCNS1 is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins.Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family.
Molecular Weight 58 kDa
Gene ID 3787
NCBI Accession NP_002242
UniProt Q96KK3
Application Notes KCNS1 antibody can be used for detection of KCNS1 by ELISA at 1:1562500. KCNS1 antibody can be used for detection of KCNS1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration 1 mg/mL
Buffer Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice As with any antibody avoid repeat freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNS1 antibody at -20 °C.
Images
Image no. 1 for anti-Potassium Voltage-Gated Channel, Delayed-Rectifier, Subfamily S, Member 1 (KCNS1) antibody (ABIN2458130) anti-Potassium Voltage-Gated Channel, Delayed-Rectifier, Subfamily S, Member 1 (KCNS1) antibody